Overview
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
5.6
USERS' SCORE
Good
Based on 9 Reviews
8.1
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Total Carbohydrate
<1 g
<1%†
Calcium (from calcium magnesium phytate)
131 mg
10%
Phosphorus (from calcium magnesium phytate)
192 mg
15%
Magnesium (from calcium magnesium phytate)
40 mg
10%
IP-6 (inositol hexaphosphate) (from calcium magnesium phytate)
800 mg
**
Inositol
220 mg
**
Top Medical Research Studies
8
Myo-inositol enhances vitamin D effects
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
Read More
4
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Read More
4
Inositol's impact on autoimmune thyroid
We set out to explore the effects of a combination of selenium and inositol on thyroid function and autoimmune characteristics in people with thyroid disorders. Through our systematic search spanning numerous databases, we reviewed studies published from 2007 to 2022, focusing on how these supplements influence thyroid health.
The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.
Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.
Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
Read More
Most Useful Reviews
7.5
Quality support
26 people found this helpful
I am very impressed with this product, which I had used before to help manage my cancer. After moving, I couldn't purchase it, and my cancer worsened, leading to two years of chemotherapy. Now, four years later, it's returning, so I ordered it as Iherb delivers here. This is a quality product that supports me at a good price. Very pleased with my purchase.
Read More
9
Enhanced defences
13 people found this helpful
After a long break due to customs issues, I resumed taking this product post-operation for my cancer. I felt a notable improvement; IP-6 and Inositol enhance my body's natural defences and promote the growth of healthy cells. Hopefully, it brings good health to you too.
Read More
7.5
Immune system boost
12 people found this helpful
I've ordered from iherb for nearly 10 years with no issues. This product is remarkable; it truly boosts my immune system and contributes positively to my health. Others have noticed thicker hair, and I’ve been overall healthier, with stable health issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
5.6
- All Researches
8
Our exploration focused on how Myoinositol, often known as Myo, impacts autoimmune disorders, particularly autoimmune thyroiditis. We learned that Myo plays a crucial role in the body's thyroid function by aiding in the production of thyroid hormones and regulating iodine, which is essential in this process.
Interestingly, when Myo was combined with Selenium in treatment, patients with subclinical hypothyroidism showed significant decreases in thyroid-stimulating hormone (TSH) levels. Additionally, levels of antithyroid autoantibodies also dropped, which is promising for those battling autoimmune thyroid issues.
However, it is important to note that the study did not exclusively isolate the effect of Myoinositol, as the results were observed in conjunction with Selenium. Therefore, while the findings are encouraging, we cannot definitively claim that Myo alone yields the same benefits in managing autoimmune disorders.
Interestingly, when Myo was combined with Selenium in treatment, patients with subclinical hypothyroidism showed significant decreases in thyroid-stimulating hormone (TSH) levels. Additionally, levels of antithyroid autoantibodies also dropped, which is promising for those battling autoimmune thyroid issues.
However, it is important to note that the study did not exclusively isolate the effect of Myoinositol, as the results were observed in conjunction with Selenium. Therefore, while the findings are encouraging, we cannot definitively claim that Myo alone yields the same benefits in managing autoimmune disorders.
Read More
8
Myo-inositol enhances vitamin D effects
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
Read More
4
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Read More
4
Inositol's impact on autoimmune thyroid
We set out to explore the effects of a combination of selenium and inositol on thyroid function and autoimmune characteristics in people with thyroid disorders. Through our systematic search spanning numerous databases, we reviewed studies published from 2007 to 2022, focusing on how these supplements influence thyroid health.
The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.
Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.
Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
Read More
4
We explored the effects of myo-inositol as part of a treatment regimen for young women with Hashimoto's thyroiditis—an autoimmune disorder. This study primarily compared the sexual functioning and depressive symptoms of women who were untreated versus those receiving various supplements including vitamin D and selenomethionine alongside myo-inositol.
While all treatment groups showed improved sexual functioning and well-being compared to the untreated women, we observed that the greatest benefits came from those receiving vitamin D. Additionally, there were no significant differences in sexual functioning and depressive symptoms between the myo-inositol and selenomethionine treatment groups.
As a result, we must note that myo-inositol's isolated effect was not clearly determined in this study due to its combination with other treatments. Therefore, while myo-inositol is seen as part of a broader therapy, its specific influence on autoimmune disorders warrants further investigation.
While all treatment groups showed improved sexual functioning and well-being compared to the untreated women, we observed that the greatest benefits came from those receiving vitamin D. Additionally, there were no significant differences in sexual functioning and depressive symptoms between the myo-inositol and selenomethionine treatment groups.
As a result, we must note that myo-inositol's isolated effect was not clearly determined in this study due to its combination with other treatments. Therefore, while myo-inositol is seen as part of a broader therapy, its specific influence on autoimmune disorders warrants further investigation.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Quality support
26 people found this helpful
I am very impressed with this product, which I had used before to help manage my cancer. After moving, I couldn't purchase it, and my cancer worsened, leading to two years of chemotherapy. Now, four years later, it's returning, so I ordered it as Iherb delivers here. This is a quality product that supports me at a good price. Very pleased with my purchase.
Read More
9
Enhanced defences
13 people found this helpful
After a long break due to customs issues, I resumed taking this product post-operation for my cancer. I felt a notable improvement; IP-6 and Inositol enhance my body's natural defences and promote the growth of healthy cells. Hopefully, it brings good health to you too.
Read More
7.5
Immune system boost
12 people found this helpful
I've ordered from iherb for nearly 10 years with no issues. This product is remarkable; it truly boosts my immune system and contributes positively to my health. Others have noticed thicker hair, and I’ve been overall healthier, with stable health issues.
Read More
7.5
Cancer management
10 people found this helpful
Despite decades of high PSA levels with no cancer found, mine started to rise again. I increased anti-cancer supplements, including IP6, and my PSA is decreasing. I find excellent information on "Cancer IP6," and I recommend doing your research.
Read More
7.5
Cancer support
8 people found this helpful
As a breast cancer patient, I was advised to boost my immune system with this product. I feel generally well but can't isolate which supplement is effective. Inositol may help regulate cellular signalling, which is essential in addressing my condition. I will reorder it.
Read More
Frequently Asked Questions
9
Enhanced defences
13 people found this helpful
After a long break due to customs issues, I resumed taking this product post-operation for my cancer. I felt a notable improvement; IP-6 and Inositol enhance my body's natural defences and promote the growth of healthy cells. Hopefully, it brings good health to you too.
9
Energy boost
3 people found this helpful
I purchased this product when I felt fatigued and unable to exercise. It provided the energy boost I needed, allowing me to stay active and accomplish tasks. I'm very satisfied with the results and will reorder, as it worked well for me.
7.5
Cancer support
8 people found this helpful
As a breast cancer patient, I was advised to boost my immune system with this product. I feel generally well but can't isolate which supplement is effective. Inositol may help regulate cellular signalling, which is essential in addressing my condition. I will reorder it.
7.5
Immune system boost
12 people found this helpful
I've ordered from iherb for nearly 10 years with no issues. This product is remarkable; it truly boosts my immune system and contributes positively to my health. Others have noticed thicker hair, and I’ve been overall healthier, with stable health issues.
6
Increased immunity
18 people found this helpful
My dog became more alert after taking this. He often had colds, and I gave him Inositol for support, which seems to have boosted his immunity remarkably. Now he’s more active and cheerful! With winter approaching, I plan to order more for him.
7.5
Cancer management
10 people found this helpful
Despite decades of high PSA levels with no cancer found, mine started to rise again. I increased anti-cancer supplements, including IP6, and my PSA is decreasing. I find excellent information on "Cancer IP6," and I recommend doing your research.
4
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
4
Inositol's impact on autoimmune thyroid
We set out to explore the effects of a combination of selenium and inositol on thyroid function and autoimmune characteristics in people with thyroid disorders. Through our systematic search spanning numerous databases, we reviewed studies published from 2007 to 2022, focusing on how these supplements influence thyroid health.
The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.
Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.
Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
8
Myo-inositol enhances vitamin D effects
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
References
- Peng B, Wang W, Gu Q, Wang P, Teng W, et al. Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis. Front Endocrinol (Lausanne). 2024;15:1445878. doi:10.3389/fendo.2024.1445878
- Yavari M, Akbari M, Ramezani Ahmadi A, Siavash Dastjerdi M, Hashemi MS. Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis. Expert Rev Endocrinol Metab. 2024;19:269. doi:10.1080/17446651.2023.2295487
- Krysiak R, Kowalcze K, Szkróbka W, Okopień B. Sexual Function and Depressive Symptoms in Young Women with Euthyroid Hashimoto's Thyroiditis Receiving Vitamin D, Selenomethionine and Myo-Inositol: A Pilot Study. Nutrients. 2023;15. doi:10.3390/nu15122815
- Paparo SR, Ferrari SM, Patrizio A, Elia G, Ragusa F, et al. Myoinositol in Autoimmune Thyroiditis. Front Endocrinol (Lausanne). 2022;13:930756. doi:10.3389/fendo.2022.930756
- Krysiak R, Kowalcze K, Okopień B. The impact of vitamin D on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in myo-inositol-treated and myo-inositol-naïve women with autoimmune thyroiditis: A pilot study. J Clin Pharm Ther. 2022;47:1759. doi:10.1111/jcpt.13730
